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Vaccinations
Vaccine reactions! Vaccination induced reactions in dogs and cats appear unexpectedly and create anxious moments for the veterinarian, pet owner and the patient. This page displays one example of a dog with a vaccine reaction to a Rabies vaccine, manufactured by a reputable and professional veterinary pharmaceutical company and administered subcutaneously as recommended. Twelve months prior to the Rabies vaccine given in this example the dog, a three year old Dachshund, was vaccinated with a multivalent vaccine containing Distemper, Hepatitis, Parainfluenza, Corona and Parvo virus antigens. A mild reaction occurred to that vaccine administration. It is unknown to which fraction of that vaccine the dog reacted.
Prior to the Rabies vaccination given in the example here, the owners were fully informed about potential vaccine reactions and what to do if another one occurred. They requested a Rabies vaccine only (they decided against giving further multivalent vaccinations) in order to conform to local ordinances and to ensure against possible infection from Rabies due to the abundant wildlife present in the dog's environment. The vaccine was administered after a discussion of potential good and undesirable effects of a vaccine.
Two hours after the Rabies vaccine was administered the dog was readmitted for itching and head-shaking, and the presence of "hives" on the dog's face and head. These eruptions on the skin, called a urticarial reaction, are rounded swollen raised areas of skin tissue that have responded locally to the administration of a substance to which the dog is allergic. Hives are caused when the body releases histamine from a cell called a Mast Cell. The Histamine then causes leaking of fluid into the surrounding body tissues from the small blood vessels and stimulates the nearby nerve endings producing the itching sensation. The dog was breathing normally but was uncomfortable. Fortunately the vast majority of vaccine reactions in the dog are similar to this case where the targeted tissue is the skin. It is very rare, but can happen, that the tracheal, laryngeal and bronchial tissues will swell causing a constricted and spastic airway. Breathing difficulty results that can be very swift in onset and have life-threatening consequences.
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